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Mesopotamia is a historical region of Western Asia situated within the Tigris–Euphrates river system, in the northern part of the Fertile Crescent. Mesopotamia is the site of the earliest developments of the Neolithic Revolution from around 10,000 BCE. It has been identified as having "inspired some of the most important developments in human history, including the invention of the wheel, the planting of the first cereal crops, and the development of cursive script, mathematics, astronomy, and agriculture". It has been known as one of the earliest civilizations to ever exist in the world. The Sumerians and Akkadians (including Assyrians and Babylonians) dominated Mesopotamia from the beginning of written history (c. 3100 BCE) to the fall of Babylon in 539 BCE, when it was conquered by the Achaemenid Empire. It fell to Alexander the Great in 332 BCE, and after his death, it became part of the Greek Seleucid Empire. Later the Arameans dominated major parts of Mesopotamia (c. 900 BCE – 270 CE).